KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3K
All Species:
9.09
Human Site:
S525
Identified Species:
20
UniProt:
Q59H18
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59H18
NP_001106279.1
936
104179
S525
S
Q
P
G
G
D
G
S
Y
V
S
V
P
S
P
Chimpanzee
Pan troglodytes
XP_513493
949
105567
S538
S
Q
P
G
G
D
G
S
Y
V
S
V
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001097254
949
105560
S538
S
Q
P
G
G
D
G
S
Y
V
S
V
P
S
P
Dog
Lupus familis
XP_537112
1087
119299
N683
P
Q
D
E
L
P
C
N
E
Y
S
Q
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5GIG6
834
92569
K439
G
K
I
K
S
M
T
K
E
K
A
D
V
L
L
Rat
Rattus norvegicus
Q7TQP6
835
92713
K440
G
K
I
K
S
M
T
K
E
K
A
D
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339957
835
92821
K440
G
K
I
K
S
M
T
K
E
K
A
D
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021182
850
93167
L455
H
D
A
I
V
A
L
L
K
H
Y
A
A
R
T
Sea Urchin
Strong. purpuratus
XP_782227
862
95496
R467
P
S
P
L
G
R
L
R
C
I
T
K
E
K
I
Poplar Tree
Populus trichocarpa
XP_002336079
539
60951
I144
Q
D
K
D
I
T
V
I
T
G
P
L
C
F
R
Maize
Zea mays
NP_001152032
543
61643
K148
D
L
S
L
E
R
R
K
I
A
D
R
N
D
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
80.1
N.A.
80.7
81.3
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
N.A.
N.A.
36.7
51.1
Protein Similarity:
100
98.3
97.2
82.6
N.A.
84.4
85.3
N.A.
N.A.
N.A.
N.A.
83.7
N.A.
N.A.
N.A.
55
65.6
P-Site Identity:
100
100
100
20
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
26.6
Percent
Protein Identity:
23.6
22.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.2
36.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
10
28
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
0
% C
% Asp:
10
19
10
10
0
28
0
0
0
0
10
28
0
10
0
% D
% Glu:
0
0
0
10
10
0
0
0
37
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
28
0
0
28
37
0
28
0
0
10
0
0
0
10
10
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
28
10
10
0
0
10
10
10
0
0
0
0
10
% I
% Lys:
0
28
10
28
0
0
0
37
10
28
0
10
0
10
0
% K
% Leu:
0
10
0
19
10
0
19
10
0
0
0
10
0
28
28
% L
% Met:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
19
0
37
0
0
10
0
0
0
0
10
0
37
0
28
% P
% Gln:
10
37
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
19
10
10
0
0
0
10
0
10
10
% R
% Ser:
28
10
10
0
28
0
0
28
0
0
37
0
0
28
10
% S
% Thr:
0
0
0
0
0
10
28
0
10
0
10
0
0
0
10
% T
% Val:
0
0
0
0
10
0
10
0
0
28
0
28
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
28
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _